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N.P.C.S. FLEXI (powder)

45 

SKU: FLEXI-EN Category:

Bone, cartilage, joint, muscle – Protection – support – strengthening

Complex superior product (with turmeric – with lactoferrin)

For daily use

MONTHLY DOSE (for a healthy, 15 bw kg / 33 lbs animal)

 

Ingredients in 1,5 g product:

 

Glucosamine sulfate…………………….. 490 mg
Fish oil powder*……………………………. 480 mg
(*containing: EPA 36 mg, DHA 18 mg)
MSM……………………………………… 180 mg
Ascorbic acid…………………………… 120 mg
Turmeric extract 95 % curcumin ……. 45 mg
Hyaluronic acid (sodium hyaluronate)………. 30 mg
Bromelain……………………………….. 30 mg
Cobalt (cobalt gluconate)………………….. 3 mg
Ribonukleáz-dúsított Lactoferrin………………………………. 18 mg
Zinc (zinc sulphate monohydrate)…………. 3 mg
Vitamin E (dl-alpha tocopheryl acetate)…….. 420 IU
Manganese (manganese gluconate)…………….. 0,4 mg

Indication:

N.P.C.S. FLEXI contains a combination of specially formulated active ingredients that are effective in preventing, alleviating or completely eliminating musculoskeletal problems in dogs. It also supports joint mobility and cartilage flexibility. Its use is recommended from a very young age for daily maintenance. In large and fast-growing dogs from puppyhood onwards, to support healthy development of bones, cartilage and tendons and to improve general mobility. For racing and working dogs, daily dosing is also recommended to relieve increased strain.

 

WARNING! In the case of illnesses with joint, bone or muscle pain, or during recovery from orthopaedic surgery, the use of N.P.C.S. FORTFLEX is recommended.

 

Dosage and route of administration:

Daily dose: Up to 15 kg (33 lbs) body weight: half a scoop / 1 heaped teaspoon (1,5 g),

16-30 kg (35-66 lbs) body weight: 1 scoop / 2 heaped teaspoon (3 g),

31-45 kg (68-99 lbs) body weight: 1.5 scoop / 3 heaped teaspoon (4,5 g).

For extra small (under 5 kg / 11 lbs) animals: ⅓ scoop / slapped teaspoon.

 

To be administered orally, mixed into food or injected dissolved in warm water.If added to dry feed, dissolve and mix in 0,5 dl of warm water.

 

Recommended duration of administration:

In healthy animals: daily use for an unlimited period. For young animals (up to 5-6 years of age), the dose may be halved after 1 month of continuous use.

For ageing animals (small: Over 8 years of age, large: over 6 years of age), the dose should not be reduced.

For puppies: normal dose

May be administered in the usual way during pregnancy and breastfeeding.

 

In case of surgery: Consult your veterinarian.

The dosage must be strictly observed!

 

Contraindications:

Not to be used in case of known hypersensitivity to any of the ingredients.

 

Side effects:

Not known.

 

Read more about the active ingredients

Lactoferrin:

Lactoferrin and bone health

It is known from numerous studies that lactoferrin promotes bone health in humans, dogs and all mammals. This protein has also been shown to be effective in supporting bone growth and increasing bone density. Lactoferrin is able to increase the activity of bone-building cells (osteoblasts) and can also inhibit bone-degrading cells (osteoclasts). With the help of lactoferrin, the bones are able to bind and store calcium (minerals), thus acting as a “mineral store” in the body.

Lactoferrin and joint health

It has two effects on joint health: it stimulates cartilage formation and it is an effective anti-inflammatory.

Cartilage formation: Cartilage is found in a myriad of places in the human and mammalian body: at the ends of bones as a component of joint surfaces, attached to ribs that form the rib cage, and in the intervertebral discs. Cartilage is made up of cartilage cells and the intercellular material (collagen and proteoglycan gel) that surrounds them. When the cartilage breaks down, the cartilage cells are unable to perform their function properly and clinical symptoms (e.g. joint pain) appear. Lactoferrin plays an important role in regulating the metabolism of cartilage cells, supporting their healthy functioning.

Reducing inflammation: Lactoferrin is present in large amounts in immune cells (neutrophil granulocytes), from which it is released in areas of inflammation. It is effective in reducing inflammation by inhibiting the synthesis of inflammation-inducing substances (IL-6, TNF) and stimulating the production of anti-inflammatory substances (IL-10)

Other beneficial properties of lactoferrin

In humans and most mammals, lactoferrin is best known as a transport molecule, but it also has numerous other functions. Lactoferrin has its own binding sites (receptors) in the digestive tract, which it interacts with to ensure the binding and absorption of metals, most importantly iron, from the intestinal tract.

Research over the past 30 years has demonstrated the beneficial effects of lactoferrin on the immune system, reproductive organs, digestive system and, last but not least, the bones.

Glucosamine sulfate:

It is a building block for cartilage production and promotes the regeneration of damaged joints. It slows down, inhibits and stops the process of cartilage erosion, and improves and maintains the viscosity of synovial fluid.

Fish oil:

Arthritis can cause unpleasant symptoms, including constant pain. Numerous studies have shown that fish oil, which is rich in omega-3 fatty acids, is highly effective in reducing the discomfort caused by arthritis, as well as the inflammation itself. It has been observed that with regular use of fish oil, joint stiffness can also be eliminated and treated.

Arthrosis, a disease in which cartilage is worn away, is much more common than rheumatoid arthritis. It usually occurs in older animals, but is often diagnosed in young ones as well. There is no definitive cure for the disease and the many drugs we use to treat the condition can have countless side effects. However, clear improvements in arthrosis, including reduced pain, reduced swelling, and reduced joint stiffness, have been reported in numerous scientific articles when administering omega-3 supplements.

MSM:

Its beneficial effects on joints have long been known. A form of organic sulphur, it is an essential source for the body to produce enzymes, antibodies, connective tissue and mucous membranes. It is also necessary for the formation of amino acids and for maintaining the molecular structure of proteins.

Ascorbic acid:

Everyone thinks of water-soluble vitamin C as the main protector of our immune system; nevertheless, bones need it too. It is essential for the formation of collagen, an important component of supporting and connective tissue, which is the basis of bone mineralisation (vitamin C deficiency can damage collagen in bones).

Turmeric:

Turmeric is a powerful anti-inflammatory herb, particularly effective in arthritis for relieving stiffness, soothing pain, and reducing inflammation in the skin and intestines.

Turmeric is very effective for joint and rheumatic complaints because it relieves joint stiffness, keeps joints flexible, strengthens cartilage and reduces oedema. It has a detoxifying and analgesic effect. It also protects cartilage from damage and should be used in cases of arthrosis.

Hyaluronic acid:

Hyaluronic acid is a natural substance with a high water-binding capacity that is found in muscles, bones and skin.

It helps to reduce friction on joint surfaces and ensures the flexibility and mobility of joints. Because its high water-binding capacity, it also ensures optimal water content in the skin and connective tissue.

Bromelain:

Bromelain is a protein-degrading (protease) enzyme naturally found in tropical pineapple, which occurs in highest concentration in the stem of the fruit.

Since 1957, a mixture of enzymes found in pineapple has been used for medical purposes because it reduces tissue oedema and greatly aids tissue and muscle regeneration and accelerates wound healing. Bromelain also supports the entire body’s defence system, boosting the production of many immune cells.

 

Cobalt:

Vitamin B12 is a relatively large molecule that is very similar to the heme-macro molecule found in red blood cells (of a similar orange-red-yellowish colour), but with a central cobalt atom (hence the name cobalamin), instead of the central iron atom found in haemoglobin. Other biologically active derivatives of this molecule are also called vitamin B12 or cobalamin. Vitamin B12 (cobalamin) is a water-soluble vitamin that plays a key role in the functioning of the brain and central nervous system and in the process of blood formation. It also plays a role in cellular metabolism, is involved in the formation of nucleic acids, influences protein synthesis in the body, promotes the incorporation of amino acids into proteins and enhances their utilisation.

 

Zinc:

Zinc is one of the minerals that should be used in small amounts, but are essential for the proper functioning of the body of small animals. Zinc contributes to bone health and can also promote bone mass growth.

Zinc is essential for new cell formation and wound healing. Zinc deficiency can reduce the rate of wound healing and increase the risk of wound infections.

 

Vitamin E:

Vitamin E functions as a fat-soluble antioxidant, protecting vulnerable fatty acids from oxidation, also known as rancidity. Excessive oxidative stress and free radical formation have been linked to a wide range of diseases, and vitamin E is key to counteracting these processes.

 

Manganese:

The benefits of manganese for the body.

It contributes to the synthesis of DNA and RNA. It is necessary for reproduction and growth. Contributes to the development of healthy bones. Manganese plays a major role in the skeletal system, development of healthy bones and proper nerve function.

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